ACUTE CAG - Prognostication of Acute Recovery Capacity in an Aging Population

ACUTE CAG is a research group comprising among others Clinical Research Centre and the Emergency Department at Copenhagen University Hospital Hvidovre and Center for Healthy Aging at the University of Copenhagen. 

Background 

It is often difficult to treat acute illness in an elderly multimorbid person because the acute illness causes imbalance to the chronic diseases the patient is already suffering from. These patients also often suffer from polypharmacy which can limit the desired effect of treatment and increase the risk of side effects. 

By using biomarkers - e.g. blood tests and information on drug consumption, lifestyle and chronic diseases – it is possible to measure a patient's biological age which provides accurate information on whether and how the patient will respond to treatment. 

ACUTE CAG 

ACUTE CAG will develop and refine the biological age measurement by identifying, combining, and testing different biomarkers. The results will be used to develop individualized treatments and personal medicines that can be used when an acute patient is hospitalized. 

For example, if a patient is hospitalized with a severe infection, and it turns out that the biological age is 20 years older than the actual age the doctors can take this into consideration when planning the treatment and rehabilitation. This increases the chances of the treatment to work out as intended, and rehospitalization can be avoided. 

30 professors are affiliated with ACUTE CAG, and biomarkers from their individual research fields will be taken into consideration when a new biological age measurement tool is developed. It is expected that the new measurement tool will contain up to 50 biomarkers and they will form an index that expresses the patient's individual recovery capacity. 

Read more

Greater Copenhagen - Clinical Academic Groups

About CAGs

Clinical Academic Groups, CAGs are appointed by the Greater Copenhagen Health Science Partners which are: The Capital Region of Denmark, Region Zealand, the Technical University of Denmark and the University of Copenhagen.

CAGs consist of researchers and clinicians from the partners' institutions, and the goal is to contribute to health care with new research results, increased quality in the clinical work and faster implementation of results.

Since 2017, four CAGs have been appointed each year. On June 4 2019, ACUTE CAG was appointed. The research group is led by Professor Ove Andersen from Clinical Research Centre, Copenhagen University Hospital, Hvidovre and Professor Lene Juel Rasmussen from Center for Healthy Aging at the University of Copenhagen.